MRCPUK SEND valid dump torrent : Endocrinology and Diabetes (Specialty Certificate Examination)

  • Exam Code: SEND
  • Exam Name: Endocrinology and Diabetes (Specialty Certificate Examination)
  • Updated: Oct 19, 2026
  • Q&As: 200 Questions and Answers

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MRCPUK SEND Exam Syllabus Topics:

SectionObjectives
Topic 1: Pituitary and Hypothalamic Disorders- Pituitary Disease
  • 1. Pituitary hormone deficiency
  • 2. Pituitary tumors
  • 3. Hypothalamic disorders
  • 4. Pituitary hormone excess
Topic 2: Calcium and Bone Metabolism- Parathyroid and Metabolic Bone Disease
  • 1. Hypoparathyroidism
  • 2. Hyperparathyroidism
  • 3. Osteoporosis
  • 4. Disorders of calcium, phosphate and vitamin D metabolism
Topic 3: General Endocrinology- Integrated Clinical Practice
  • 1. Endocrine hypertension
  • 2. Neuroendocrine disorders
  • 3. Investigation, imaging and interpretation of endocrine tests
  • 4. Genetic endocrine syndromes
Topic 4: Diabetes Mellitus- Complications
  • 1. Macrovascular complications
  • 2. Acute metabolic emergencies
  • 3. Perioperative and inpatient diabetes management
  • 4. Microvascular complications
- Diagnosis and Classification
  • 1. Type 1 diabetes
  • 2. Other specific types of diabetes
  • 3. Type 2 diabetes
  • 4. Gestational diabetes
- Management
  • 1. Technology and glucose monitoring
  • 2. Oral and injectable therapies
  • 3. Insulin therapy
  • 4. Lifestyle interventions
Topic 5: Reproductive Endocrinology- Gonadal Disorders
  • 1. Disorders of puberty and fertility
  • 2. Polycystic ovary syndrome
  • 3. Male hypogonadism
  • 4. Female reproductive endocrinology
Topic 6: Adrenal Disorders- Adrenal Disease
  • 1. Cushing syndrome
  • 2. Adrenal insufficiency
  • 3. Primary aldosteronism
  • 4. Pheochromocytoma and adrenal incidentaloma
Topic 7: Thyroid Disorders- Thyroid Disease
  • 1. Hypothyroidism
  • 2. Thyroid nodules and cancer
  • 3. Hyperthyroidism
  • 4. Thyroiditis and special clinical situations

MRCPUK Endocrinology and Diabetes (Specialty Certificate Examination) Sample Questions:

Question #1

A 36-year-old woman was seen in the clinic with a recurrence of hyperthyroidism after a 2year remission. She had been treated with carbimazole for 18 months following her original presentation. She was moderately symptomatic and was keen to be treated in the same way again. She was planning a pregnancy.
Investigations: serum prolactin240 mU/L (<360) serum thyroid-stimulating hormone<0.1 mU/L (0.4-5.0) serum free T428.0 pmol/L (10.0-22.0)
anti-thyroid-stimulating hormone receptor antibodies44 U/L (<7)
What is the most appropriate next step in management?

  • A. block-and-replace treatment with carbimazole and levothyroxine
  • B. carbimazole
  • C. radioiodine treatment
  • D. propylthiouracil
  • E. referral for thyroidectomy
Reveal Solution  Discussion  0

Correct Answer: D  🗳️

Question #2

A 16-year-old boy was referred to the endocrine clinic with symptoms of delayed puberty.
On examination, he had a reduced sense of smell, small-sized testes and underdeveloped
secondary sexual characteristics.
Investigations:
serum testosterone3.5 nmol/L (9.0-35.0)
serum follicle-stimulating hormone1.0 U/L (1.0-7.0)
serum luteinising hormone1.5 U/L (1.0-10.0)
serum prolactin220 mU/L (<360)
MR scan of brainnormal
He asked about his future fertility.
What will be the most useful agent for him to achieve fertility?

  • A. testosterone
  • B. gonadotropin-releasing hormones
  • C. bromocriptine
  • D. clomifene
  • E. octreotide
Reveal Solution  Discussion  0

Correct Answer: B  🗳️

Question #3

A 15-year-old boy was referred by the school nurse because she was concerned about his weight. There was no past history of note. He was not taking any medication. His height was 1.61 m and he weighed 70.5 kg.
Investigations: growth chartsee image

What is the most likely diagnosis?

  • A. Prader-Willi syndrome
  • B. growth hormone deficiency
  • C. simple obesity
  • D. Cushing's disease
  • E. leptin deficiency
Reveal Solution  Discussion  0

Correct Answer: D  🗳️

Question #4

A 62-year-old woman with persistent hypertension attended the clinic for review. She had no previous medical history of note and was taking amlodipine, ramipril, bendroflumethiazide, spironolactone and doxazosin. Her blood pressure was raised at 160/100 mmHg.
Investigations:
serum sodium138 mmol/L (137-144)
serum potassium3.8 mmol/L (3.5-4.9)
A blood test for renin and aldosterone concentration was being considered.
For what minimum period should spironolactone be discontinued before this test?

  • A. 6 weeks
  • B. 1 week
  • C. 8 weeks
  • D. 2 weeks
  • E. 72 h
Reveal Solution  Discussion  0

Correct Answer: A  🗳️

Question #5

A 19-year-old man was seen in the diabetes clinic. He had lost 2 kg in weight since the diagnosis of diabetes mellitus 18 months previously. At presentation, his body mass index was 33 kg/m2 (18-25), his random plasma glucose was 18.0 mmol/L and his haemoglobin A1c was 56 mmol/mol (20-42). He was taking gliclazide, and metformin had been added later. His father and grandfather had developed diabetes mellitus during their twenties.
Investigations:
haemoglobin A1c56 mmol/mol (20-42)
serum C-peptide301 pmol/L (180-360)
anti-glutamic acid decarboxylase (GAD)
antibodiesnegative
What is the most likely diagnosis?

  • A. type 1 diabetes mellitus
  • B. type 2 diabetes mellitus
  • C. maturity-onset diabetes of the young
  • D. latent-onset diabetes of autoimmunity
  • E. chronic pancreatitis
Reveal Solution  Discussion  0

Correct Answer: C  🗳️

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